Liver cancer models
  • Orthotopic transplantation of intact tissue
  • Metastatic sites
    • lymph nodes
    • liver
    • lung
    • peritoneum
  • Green Fluorescent Protein expression

1.   Sun, F.X., Tang, Z.Y., Liu, K.D., Ye, S.L., Xue, Q., Gao, D.M., and Ma, Z.C. Establishment of a metastatic model of human hepatocellular carcinoma in nude mice via orthotopic implantation of histologically intact tissues. Int. J. Cancer 66, 239-243, 1996.

2. Sun, F-X., Tang, Z-Y., Liu, K-D., Xue, Q., Gao, D-M., Yu, Y-Q., Zhou, X-D., Ma, Z-C. Metastatic models of human liver cancer in nude mice orthotopically constructed by using histologically intact patient specimens. J. Cancer Res. Clin. Oncol. 122, 397-402, 1996.

3. Rashidi, B., An, Z., Sun, F-X, Li, X-M., Tang, Z.Y., Moossa, A.R., and Hoffman, R.M. Efficacy of intra-hepatectomy 5-FU on recurrence and metastasis of human hepatocellular carcinoma in nude mice. Int. J. Cancer 91, 231-235, 2001.